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Abstract : |
Natural bone consisted of calcium phosphate with nanometer-sized needle-like crystals ofapproximately 5-20 nm width by 60 nm length. Synthetic calcium phosphates and Bioglass arebiocompatible and bioactive as they bond to bone and enhance bone tissue formation. This property isattributed to their similarity with the mineral phase of natural bone except its constituent particle size.Calcium phosphate ceramics have been used in dentistry and orthopedics for over 30 years because ofthese properties. Several studies indicated that incorporation of growth hormones into these ceramicmatrices facilitated increased tissue regeneration. Nanophase calcium phosphates can mimic thedimensions of constituent components of natural tissues; can modulate enhanced osteoblast adhesionand resorption with long-term functionality of tissue engineered implants. This mini review discussessome of the recent developments in nanophase ceramic matrices utilized for bone tissue engineering., |
