Home

Identification Structural and Functional Characterization of a New Early Gene (6A3-5 7 kb): Implication in the Proliferation and Differentiation of Smooth Muscle Cells


Author(s) : L. John Garin Gwenaële Zibara Kazem, 
Publisher : N/A
Publication Date : 2005
ISSN : N/A
Abstract : Arterial smooth muscle cells (SMCs) play a major role in atherosclerosis and restenosis. Differential display was used to compare transcription profiles of synthetic SMCs to proliferating rat cultured SMC line. An isolated cDNA band (6A3-5) was shown by northern (7 kb) to be upregulated in the proliferating cell line. A rat tissue northern showed differential expression of this gene in different tissues. Using 5