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Infection with Hepatitis C Virus among HIV-Infected Pregnant Women in Thailand


Author(s) : McConnell Michelle S. Sanay Chearskul Jeffrey Wiener Wimol Siriwasin Kuhnert Wendi L. Supapol Wendy Bhanich Tawee Chotpitayasunondh Bower William A. Anuvat Roongpisuthipong Thanyanan Chaowanachan Natapakwa Skunodom Jamieson Denise J, 
Publisher : N/A
Publication Date : 2009
ISSN : N/A
Abstract : Objective. The purpose of this study was to describe the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among a cohort of pregnant Thai women. Methods. Samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies in Bangkok, Thailand, were tested for HCV. Results. Among HIV-infected pregnant women, HCV seroprevelance was 3.8% and the active HCV infection rate was 3.0%. Among HIV-uninfected pregnant women, 0.3% were HCV-infected. Intravenous drug use by the woman was the factor most strongly associated with HCV seropositivity. Among 48 infants tested for HCV who were born to HIV/HCV coinfected women, two infants were HCV infected for an HCV transmission rate of 4.2% (95% 0.51أƒآ¢أ‚€أ‚“14.25%). Conclusions. HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women.,