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Hyperhomocysteinemia presenting as superior mesenteric artery thrombosis


Author(s) : Shallam James Balakrishnan R Rajnish R Alexander Thomas, 
Publisher : N/A
Publication Date : 2005
ISSN : N/A
Abstract : We report a 23-year-old man who presented with acute abdomen. At laparotomy, he was diagnosed to have superior mesenteric artery thrombosis, with consequent extensive intestinal gangrene extending from the proximal jejunum till the mid transverse colon. He subsequently developed dry gangrene of the digits. Further evaluation showed that he had marked hyperhomocysteinemia. The gangrenous bowel was resected, and the homocysteine level normalized with folic acid supplementation. He is well at 1-year follow up. His brother, who was asymptomatic, was also detected to have hyperhomocysteinemia, which responded to folic acid.[,