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Abstract : |
Effects of exercise on different body systems, especially cardiovascular and musculoskeletal systems have been proven. In the haemostatic system the influence of training has been extensively studied but there are a few investigations that analyze the effects of training programs on coagulation factors. In this study we have surveyed the effect of physical fitness on coagulation factors in healthy young men. Subjects were 26 young men without any history of cardiac, coagulation or respiratory problems in themselves or their immediate family, a cardiologist confirmed their cardiovascular health. These men were divided in two groups; the physically active group (Ac) and the sedentary group (Se). The groups were similar in life style except their activity. The physically active men (Ac; n=10) were involved in regular exercise at least three times a week during the last six months. The sedentary men (Se; n = 16) did not participated in any sport activity. According to preliminary clinical examinations, Anthropometric variables had no significant differences in either group, but the Bruce test and a standardized ergometery test proved that functional capacity of cardiovascular system in the Ac group is significantly higher than the Se group. Blood data analysis showed that the basal levels of FVIII:c and FIX:c were significantly higher in the Ac group. FVIII:c, FIX:c, fibrinogen and vWF:ac increased in response to exercise while vWF:ag, FVII:c and aPTT decreased significantly. All of these parameters, except fibrinogen, FVIII:c and vWF:ag, returned to resting values during passive recovery. In the Se group elevation in vWF:ag during active recovery, reduction of aPTT and elevation of FVIII:c and FIX:c during passive recovery was statistically significant. Active and sedentary young men are different in resting values of some coagulation factors and their coagulation markers also vary in response to a submaximal exercise program on cycle ergometer. This is due to the difference between physical fitness levels of these two groups. Considering the unfavorable effects of imbalance between coagulation and fibrinolysis, it seems in any type of physical activity especially sport activities the haemostatic balance should be evaluated. Controlling the markers of these systems will help us improve safety of patients in whom exercise is a part of their rehabilitation program, this way it will be possible to enhance positive effects and reduce the possible risks of professional sports for healthy individuals., Effects of exercise on different body systems, especially cardiovascular and musculoskeletal systems have been proven. In the haemostatic system the influence of training has been extensively studied but there are a few investigations that analyze the effects of training programs on coagulation factors. In this study we have surveyed the effect of physical fitness on coagulation factors in healthy young men. Subjects were 26 young men without any history of cardiac, coagulation or respiratory problems in themselves or their immediate family, a cardiologist confirmed their cardiovascular health. These men were divided in two groups; the physically active group (Ac) and the sedentary group (Se). The groups were similar in life style except their activity. The physically active men (Ac; n=10) were involved in regular exercise at least three times a week during the last six months. The sedentary men (Se; n = 16) did not participated in any sport activity. According to preliminary clinical examinations, Anthropometric variables had no significant differences in either group, but the Bruce test and a standardized ergometery test proved that functional capacity of cardiovascular system in the Ac group is significantly higher than the Se group. Blood data analysis showed that the basal levels of FVIII:c and FIX:c were significantly higher in the Ac group. FVIII:c, FIX:c, fibrinogen and vWF:ac increased in response to exercise while vWF:ag, FVII:c and aPTT decreased significantly. All of these parameters, except fibrinogen, FVIII:c and vWF:ag, returned to resting values during passive recovery. In the Se group elevation in vWF:ag during active recovery, reduction of aPTT and elevation of FVIII:c and FIX:c during passive recovery was statistically significant. Active and sedentary young men are different in resting values of some coagulation factors and their coagulation markers also vary in response to a submaximal exercise program on cycle ergometer. This is due to the difference between physical fitness levels of these two groups. Considering the unfavorable effects of imbalance between coagulation and fibrinolysis, it seems in any type of physical activity especially sport activities the haemostatic balance should be evaluated. Controlling the markers of these systems will help us improve safety of patients in whom exercise is a part of their rehabilitation program, this way it will be possible to enhance positive effects and reduce the possible risks of professional sports for healthy individuals., |
