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Abstract : |
Streptococcus pyogenes (group A streptococcus) is one of the most common human pathogens. It causes a wide array of infections, the most frequent of which is acute pharyngitis (strep throat). From the late 1980s, Streptococcal Toxic Shock-like Syndrome (STSS) caused by S. pyogenes became a serious problem in both developed and developing countries. Symptoms such as pharyngitis, fever and pain may suddenly develop and the disease may progress very rapidly in some patients to soft tissue necrosis, acute kidney failure, Adult Respiratory Distress Syndrome (ARDS), Disseminated Intravascular Coagulopathy (DIC) and Multiorgan Failure (MOF), leading to shock and death. In this review, characterization of genotypes and antimicrobial susceptibility of strains isolated from patients of severe invasive streptococcal infections are summarized., |
