A chemically defined medium for production of actinomycin D by Streptomyces parvulus
| Author(s) : | Nei Pereira Jأ؛nior Edison Lopes Carlos, |
| Publisher : | N/A |
| Publication Date : | 2001 |
| ISSN : | N/A |
| Abstract : | A chemically defined medium consisting of D(+)fructose, L(-)threonine, K2HPO4, MgSO4.7H2O, ZnSO4.7H2O, CaCl2.2H2O, FeSO4.7H2O and deionized water, was developed to maximize the synthesis of actinomycin D by the Streptomyces parvulus DAUFPE 3124 strain. This medium resulted in the maximum antibiotic concentration of 133mg/L while using the original medium the production of actinomycin D was poor not surpassing 43mg/L., |